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Effect of Mitoxantrone on MRI in Progressive MS, Results of the MIMS Trial
Neurol 65:690-695, Krapf,H.,et al, 2005
See this aricle in Pubmed

Article Abstract
In the MIMS trail 12 mg/m2 Mx does not reduce the number of MRI scans with positive Gd enhancement at month 12 and 24 vs placebo. Results of secondary MRI outcome measures are suggestive of a positive impact of 12 and 5 mg/m2 Mx on some of the Gd enhanced and unenhanced MRI measures as expected from other Mx MRI studies in the past.
 
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immunosuppressive agents
mitoxantrone
MRI
MRI,abnormal
multiple sclerosis
multiple sclerosis,chronic progressive
multiple sclerosis,secondary progressive
multiple sclerosis,treatment of
treatment of neurologic disorder

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